A study on Litsea monopetala for evaluating its pharmacological properties
نویسندگان
چکیده
Aims: To assess the cytotoxicity, thrombolytic, anthelmintic and antioxidant activity of mehanol extract Litsea monopetala (Family: Lauraceae) leaves in laboratory using vitro methods.Methods: Cytotoxicity test was done by brine shrimp lethality bioassay where concentration 400, 200, 100, 50, 25, 12.5, 6.25, 3.125, 1.5625, 0.78125 (µg/ml). In thrombolytic performed clot lysis method 2.5, 5, 10 20 (mg/mL) saline water. Anthelmintic adult earthworms 10, 20, 40, 60, 80 (mg/ml) were used. Finally determined total phenolic content determination Folin-Ciocalteu reagent.Result: The showed cytotoxic against nauplii LC50 value 41.05(µg/ml) investigated our research 9.52, 9.49, 13.64 17.50 %  respectively as % lysis. paralysis time at 76.75 min, 60 51.75 44.5 min 64.5 death 90.50min, 63.75min, 55.50min, 44.75min 71min. respectively. displayed significant which 20.75 (mg GAE / gm) extracts.Conclusions: activities observed could be attributed to presence some phytochemicals have been related with cytotoxic, property.
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ژورنال
عنوان ژورنال: Discovery phytomedicine
سال: 2021
ISSN: ['2368-4798']
DOI: https://doi.org/10.15562/phytomedicine.2021.159